What is the recommended oxygen saturation target for most patients requiring supplemental oxygen?

The recommended oxygen saturation target for most patients requiring supplemental oxygen is typically between 92% to 96%. This range is considered optimal for ensuring adequate oxygen delivery to tissues while minimizing the risk of hyperoxia, which can occur if saturation levels exceed 96%. Maintaining oxygen saturation within this target range helps to provide sufficient oxygen for cellular metabolism and prevent complications associated with both low oxygen levels (hypoxemia) and excessively high levels of oxygen.

In clinical practice, targeting oxygen saturations below 92% may not provide adequate oxygenation for patients, especially those with respiratory conditions. Conversely, aiming for saturations above 96% could potentially lead to adverse effects, particularly in certain populations, such as patients with chronic obstructive pulmonary disease (COPD), where elevated oxygen levels can inhibit the patient's drive to breathe. Therefore, the range of 92% to 96% strikes a balance between the need for adequate oxygenation and safety for the patient.