Which of the following indicates a need for oxygen therapy?

The indication of a need for oxygen therapy is closely tied to the body's ability to adequately oxygenate its tissues. Restlessness and confusion are clinical signs that often suggest inadequate oxygenation, also known as hypoxemia. When the brain is not receiving enough oxygen, it can lead to altered mental states, including restlessness, confusion, or even more severe cognitive impairments.

These symptoms are crucial indicators that the patient may be experiencing respiratory distress or compromised oxygen levels, necessitating the use of supplemental oxygen to improve their condition. Addressing this potential hypoxemia with oxygen therapy can help ensure that organs and tissues receive the oxygen they need to function properly and alleviate these concerning symptoms.

The other options, such as increased appetite, normal blood pressure, and a stable heart rate, do not signal a need for oxygen therapy. Normal physiological functions in these areas generally indicate that the body is coping well, hence they do not suggest a significant demand for supplemental oxygen.